Located along the Tennessee River, Muscle Shoals, Alabama, is the unlikely breeding ground for some of America's most creative and defiant music. Under the spiritual influence of the “Singing River,” as Native Americans called it, the music of Muscle Shoals changed the world and sold in the millions. At its heart is FAME Studios founder Rick Hall, who overcame crushing poverty and staggering tragedies to bring black and white together to create the music which would give birth to the “Muscle Shoals sound.” Mick Jagger, Keith Richards, Percy Sledge, Gregg Allman, Clarence Carter, Etta James, Alicia Keys, Bono, and others bear witness to the magnetism and mystery of Muscle Shoals—and why it remains influential today.