Nanni Moretti joins forces with the great French actor Michel Piccoli to tell the story of Melville, a cardinal who suddenly finds himself elected as the next Pope. Never the front runner and completely caught off guard, he panics as he's presented to the faithful in St. Peter's Square. To prevent a world wide crisis, the Vatican's spokesman calls in an unlikely psychiatrist who is neither religious or all that committed, played by Moretti, to find out what is wrong with the new Pope. But Cardinal Melville is adamant: he does not want the job, or at least needs time to think it over. What follows is a marvelous insight into the concept of a human being existing behind the title of God's representative on Earth.